curaTime
News und Events
  • curATalk Heinz Handels - 16.01.2025

    AI in Medical Image Computing

    16.01.2025, 5:00 - 5:45 PM

    Prof. Heinz Handels

    Department of Artificial Intelligence in Medical Image and Signal Processing, DFKI Lübeck

    Institute of Medical Informatics, University of Lübeck

     

  • Register now for our next 2.5 days (Bio-) Hackathon “curAHack” on March 31 - April 02.2025 in Mainz

    Interdisciplinary hacking, problem solving and networking: The event is open to all disciplines and career levels (students are welcome!). During the hacking sessions, you will be supported by a mentor. The best teams will win prizes.

    We are looking forward to seeing you in spring!

    Check out our 5 challenges here: curahack-challenges-2025.pdf

  • curATalk Miguel Andrade - 02.12.2024

    „Computational approaches for the prediction of gene and protein function“

    02.12.2024, 5:00 - 5:45 pm

    Prof. Miguel Andrade

    Computational Biology and Data Mining Group, JGU Mainz

    Das Seminar will be held on-site at TRON gGmbH, Goettelmannstrasse 17, Mainz, seminar room ground floor right .

  • curATalk Martin Zörnig - 26.11.2024

    Introducing ForTra - Promoting the translation  of medical research results into clinical application

    26.11.2024, 17 - 17:45 Uhr

    Prof. Dr. Martin Zörnig

    ForTra gGmbH für Forschungstransfer der Else-Kröner-Fresenius-Stiftung, Bad Homburg v.d. Höhe

  • Vernetzungsveranstaltung der BioVation RLP - wir sind mit dabei!

    Markus Junker, unser Mitglied im curATime-Management Team, vom DFKI leitet den Workshop „KI in Life Sciences: Potenziale und Herausforderungen“, in dem unser Clustersprecher Prof. Johnny Kim curATime vorstellen wird. Außerdem beteiligt sich Prof. Andreas Dengel, Geschäftsführender Direktor des DFKI, an der Podiumsdiskussion "Vernetzung regionaler Technologiezentren in RLP" und unser curATime Projektleiter und Lotse für KI und Life Science, Prof. Stefan Kramer von der Johannes Gutenberg-Universität spricht über “KI und Life Science in Rheinland-Pfalz”.

Upcoming Events

2.5 days (Bio-) Hackathon “curAHack” at Gutenberg Digital Hub in Mainz: March 31 - April 02.2025

Interdisciplinary hacking, problem solving and networking: Everyone is welcome - with and without programming skills and at all career levels! 5 challenges are waiting for you: Take a look at the descriptions: curahack-challenges-2025.pdf

A mentor will be at your and your team's side during the hackathon. The best team wins a prize!

Register here free of charge and choose a challenge, we look forward to seeing you!

1st curATime Career Day for Junior Scientists

When: 10.03.2025 9:00 - 17:15 Uhr

Audience: PhD students, early Postdocs

Where: University Medical Center Mainz, Building 708

Registration: Send this form to [javascript protected email address]

Take the unique opportunity and participate in one of the two workshops and at our panel discussion! At the discussion, you will have the chance to learn about various career options and paths by our curATime cluster members and you will get personal and inspiring insights.

Workshop 1: The art of engaging small talk

Workshop 2: Transferable Skills for your Career

Panel Discussion:

Life Science Zentrum Mainz (LZM): Christina tom Suden

AI Start-up/ Industry: tba

BioNTech: XiaoXing Qing

Young Group Leader/Academia: tba

curATalk Seminar Series

The curATalk lecture series was created in 2021 in order to connect the scientists that are involved in curATime as well as thematically closely related scientist and their research. This virtual meeting takes place at regular intervals and presents their latest research findings and topics that provide additional scientific value for the individual curATime projects. The curATalks are announced publicly and enjoy lively participation from a broad audience.

curATalks
  • curATalk Heinz Handels - 16.01.2025

    AI in Medical Image Computing

    16.01.2025, 5:00 - 5:45 PM

    Prof. Heinz Handels

    Department of Artificial Intelligence in Medical Image and Signal Processing, DFKI Lübeck

    Institute of Medical Informatics, University of Lübeck

     

  • curATalk Miguel Andrade - 02.12.2024

    „Computational approaches for the prediction of gene and protein function“

    02.12.2024, 5:00 - 5:45 pm

    Prof. Miguel Andrade

    Computational Biology and Data Mining Group, JGU Mainz

    Das Seminar will be held on-site at TRON gGmbH, Goettelmannstrasse 17, Mainz, seminar room ground floor right .

  • curATalk Martin Zörnig - 26.11.2024

    Introducing ForTra - Promoting the translation  of medical research results into clinical application

    26.11.2024, 17 - 17:45 Uhr

    Prof. Dr. Martin Zörnig

    ForTra gGmbH für Forschungstransfer der Else-Kröner-Fresenius-Stiftung, Bad Homburg v.d. Höhe

  • curATalk Bernd Engelmann - 06.11.2024

    „Immune cell specificity of immunothrombosis control“

    06.11.2024, 5:15 - 6 pm

    Prof. Bernd Engelmann

    Institute for Laboratory Medicine,
    University Hospital of Munich (LMU Klinikum)

    The seminar will take place on-site at the University Medical Center Campus Mainz Building 708, Seminar room 2.

  • curATalk Lena Seegers - 31.10.2024

    Sex differences in coronary artery disease

    31.10.2024, 17:00 - 18:00 Uhr

    Dr. Lena Seegers

    Universitätsklinikum Frankfurt am Main, Medizinische Klinik 3: Kardiologie, Angiologie

    The seminar will be held on-site at the University Medical Center Mainz Campus, building 102, seminar room 1.

  • curATalk Laura Zelarayán-Behrend - 02.10.2024

    Restoration of endogenous transcription factor activity by CRISPRa to prevent cardiac failure

    02.10.2024, 17 - 18:00 Uhr

    Prof Laura Zelarayán

    Institute of Phamacology and Toxicology,

    University Medical Center Göttingen

    The seminar will be held on-site at the University Medical Center Mainz, Building 708

  • curATalk Florian A. Weinberger - 02.10.2024

    Pluripotent stem cell derived cardiomyocytes for cardiac repair - pharmacological considerations

    02.10.2024, 17 - 18:00 Uhr

    Dr Florian A. Weinberger

    Spanish National Center for Cardiovascular Research, Madrid

    & Medical Center Hamburg-Eppendorf

    The seminar will be held on-site at University Medical Center Mainz, Building 708

  • curATalk Alice Assinger - 13.06.2024

    Platelets in Infection: A Battle of Wits

    13.06.2024, 17:15 - 18:15

    Prof. Dr. Alice Assinger

    Institute of Vascular Biology and Thrombosis Research,

    Medical University of Vienna, Austria

    The seminar will be held on-site at University Medical Center Mainz, Building 708

  • curATalk Gwendalyn Randolph - 08.05.2024

    Dissemination of inflammatory cells and molecules from the intestine to downstream and distal organs

    08.05.2024, 17 - 17:45 Uhr

    Prof. Dr. Gwendalyn Randolph

    Emil R. Unanue Professor of Immunobiology, Department of Pathology

    Washington University in St. Louis, USA

  • curATalk Laura Bindila - 18.04.2024

    Modern lipidomics approaches for clinical and preclinical research and profiling

    18.04.2024, 17 - 17:45 Uhr

    Dr. Laura Bindila

    Clinical Lipidomics Unit, Institute of Physiological Chemistry

    University Medical Center Mainz

  • curATalk Stefan Engelhardt - 15.01.2024

    Macrophage-targeted RNA therapeutics

    15.01.2024, 17 - 17:45 Uhr

    Prof. Dr. Dr. Stefan Engelhardt

    Institute of Pharmacology and Toxicology

    Technical University of Munich

    Speaker of the CNATM Cluster

  • curATalk Christoph Reinhardt - 08.11.2023

    Microbiota and Arterial Thrombosis

    08.11.2023, 17 - 17:45 Uhr

    Jun.-Prof. Dr. Christoph Reinhardt

    Center for Thrombosis and Haemostasis

    University Medical Center Mainz, Germany

  • curATalk Muhammad Nabeel Asim - 08.08.2023

    Protein Protein interaction prediction in our AI based Genomics and Proteomics Sequence Analysis Framework

    08.08.2023, 17 - 17:45 Uhr

    Dr. Muhammad Nabeel Asim

    DFKI GmbH

    Kaiserslautern, Germany

  • curATalk Klaus Ley - 12.06.2023

    Breaking Tolerance: The Autoimmune Aspect of Atherosclerosis

    12.06.2023, 17 - 17:45 Uhr

    Prof. Dr. Klaus Ley

    Immunology Center of Georgia

    Augusta University, USA

  • curATalk Johnny Kim - 25.05.2023

    Synthetic regeneration at the heart of reversible reprogramming

    25.05.2023, 17:00 - 17:45 Uhr

    Dr. Johnny Kim

    TRON gGmbH, Mainz

  • curATalk Christoph Binder - 23.11.2022

    „Humoral“ Immunity and Immune Homeostasis in Atherosclerosis

    23.11.2022, 17:00 - 17:45 Uhr

    Prof. Dr. Christoph Binder
    Department of Laboratory Medicine Medical University of Vienna & Center for Molecular Medicine of the Austrian Academy of Sciences

  • curATalk Markus Jostock - 21.03.2023

    Blockchain as Digital Access Gate to Medical Data

    21.03.2023, 17:00 - 17:45 Uhr

    Dr. Markus Jostock

    Arxum GmbH, Kaiserslautern

  • curATalk David Leistner - 17.01.2023

    Acute coronary syndrome – novel pathophysiologic insights call for precision prevention

    17.01.2023, 17:00 - 17:45 Uhr

    Prof. Dr. David M. Leistner

    Med. Clinic 3 – Cardiology, Angiology, University Hospital Frankfurt

  • curATalk Lutz Nuhn - 06.09.2022

    Macromolecular strategies for enhancing immunotherapy responses to treat cardiovascular diseases

    06.09.2022, 17:00 - 17:45 Uhr

    Prof. Lutz Nuhn

    Julius Maximilian University Würzburg

  • curATalk Florian Leuschner - 21.07.2022

    Inflammation of the heart: Mechanism and therapeutic options

    21.07.2022, 16:00 – 16:45 Uhr

    Prof. Dr. med. Florian Leuschner

    Heidelberg University Hospital

  • curATalk Hugo ten Cate - 21.06.2022

    Atherothrombosis: the impact of clotting proteases
    21.06.2022 17:30 - 18:15 Uhr
    Prof. Hugo ten Cate
    CARIM, Maastricht University Medical Center+

  • curATalk Stefanie Dimmeler - 12.04.2022

    RNA therapeutics in cardiovascular disease

    12.04.2022, 17:00 - 18:00 Uhr

    Prof. Dr. Stefanie Dimmeler

    Goethe- University, Frankfurt

    Institute of Cardiovascular Regeneration, Centre for Molecular Medicine

  • curATalk Johan Trygg - 23.03.2022

    Chemometrics strategies and tools in Precision Medicine

    23.03.2022 17:30 - 18:15 Uhr

    Prof. Johan Trygg

    Departmentof Chemistry, Umeå University, Umeå, Sweden

    Corporate Research, Sartorius, Umeå, Sweden

  • curATalk Jürgen Scheele - 22.03.2022

    Artificial CRISPR, an AI based approach to predict signature drug response from multi-omics datasets

    22.03.2022, 17:30 - 18:15 Uhr

    Prof. Dr. Jürgen Scheele

    Chief Medical Officer Innoplexus AG

  • curATalk Abdelhak Zoubir - 15.02.2022

    Advancing Robust Signal Processing and Statistical Learning for Biomedical Applications

    15.02.2022, 17:30 - 18:15 Uhr

    Prof. Dr.-Ing. Abdelhak Zoubir

    Signal Processing Group, Technical University of Darmstadt

  • curATalk Sara Vieira-Silva - 02.02.2022

    Human gut microbiota variation in health and disease

    02.02.2022, 17:00 – 17:45 Uhr

    Sara Vieira-Silva, PhD

    Laboratory of Molecular Bacteriology (Rega Institute), KU Leuven, Belgium

  • curATalk Jama Nateqi - 24.01.2022

    Symptoma – Every patient deserves the right diagnosisand treatment

    24.01.2022, 17:00 - 17:45 Uhr

    Dr. med-univ. Jama Nateqi

    Symptoma GmbH

  • curATalk Stefan Tenzer - 15.12.2021

    Mass spectrometry-based proteomics in translational research and systems medicine
    15.12.2021, 17:30 – 18:15 Uhr
    Univ.-Prof. Dr. rer. nat. Stefan Tenzer
    Institut für Immunologie, Universitätsmedizin Mainz

curAMeet 2024 - Our First Cluster Conference

Translating Research into Therapies” was the motto of our first cluster conference on February 6th, which brought together all cluster stakeholders to discuss current research issues and results in a relaxed atmosphere.

External experts from a variety of fields such as translational research, AI, thrombosis research and sustainability in science not only gave our members fresh perspectives with their presentations, but also expanded our network. In addition, renowned speakers from politics and BMBF representatives once again highlighted the importance of our cluster and reinforced our joint mission.

Afterwards, our lighthouse projects were presented within short presentations and all of our other curATime projects were discussed intensively during the poster session - a very good opportunity to strengthen personal contacts within the cluster.

Our conference day ended by handing out the “curAEquality” award: we awarded special research achievements in the field of gender and diversity for the first time. The winner, Romina Wolz, who is currently working on her doctoral thesis at the Center for Thrombosis and Haemostasis at the University Medical Center Mainz, received the award for her curATime sub-project “Role of macrophage coagulation signaling in atherosclerosis”.

Postersession at the curAMeet 2024

curAHack - 1st curATime Hackathon

Innovate the future of Life Science and Medicine

curAHack has brought together young scientists, bioinformaticians and healthcare-enthusiasts to tackle research challenges from the curATime cluster. With guidance from mentors and experts, participants have developed innovative solutions presented their ideas to a jury at the end of the event. More information about the challenges and the event itself can be found here.

The mentors of the three challenges draw an enthusiastic conclusion:

"Team 1 , "curAGUI" was required to create a GUI that was able to implement all of the placeholder scripts provided in order to further on be able to replace them with trained deep learning models. The team was able to develop a basic framework that meant to envelop all of the required points and integrated videos in a manner that would mimic the results of the pipeline."

Aida Romano Martínez, University Medical Center Mainz

"During the hackathon, two teams worked on an RNA-seq analysis pipeline that should not require any gene annotation information for initial analysis. Both teams were able to conduct exploratory analysis to quantify the effect of different ensemble gene annotation models. As a solution, both teams came up with k-mer count tables as an intermediate result file that can later be mapped to any gene annotation.

While one team, the "Bioinformagicians", established an analysis pipeline using existing tools that they cleverly selected and adapted for the intended use, the other team, the "Expressionists", developed a novel analysis from scratch. The Bioinformagicians ultimately won the hackathon with a combined analysis that could be the basis for the development of novel expression pipeline for RNA-seq data. We will summarize all results and findings in a preprint and make all data, code, and analysis available as public repository and on a preprint server."

Dr. David Weber, TRON gGmbH

"The Hackathon challenge “Target Sequence for RNA delivery” was tackled by the team “CurApollo13” that aimed to identify peptide sequences that could enable targeted delivery of nanoparticles to endothelial cells within atherosclerotic lesions. Without any prior knowledge or computational resources, the team came up with two creative and yet complementary concepts. One approach involved analysis of 3D protein structures of paratope/epitope pairs.

In a second approach, the CurApollo13-team provided a concept wherein 3D structures of random short peptide sequences could be computationally predicted using AlphaFold, a powerful computational method that can simulate 3D protein structures. Conceptually, these putative structures could be superimposed on to antigens to test their putative binding. In principle, the first approach could be used to validate the second, fully computational approach.  Team CurApollo13 finished as the runners-up of the curAHack."

Dr. Johnny Kim, TRON gGmbH

curAHack 2024 at the Gutenberg Digital Hub at the Zollhafen Mainz.